Microbiome Analytics
The gut microbiota, characterized as the microbiome, plays a pivotal role in human health, function, and disease. Our primary research focus is to characterize patterns in microbiome imbalance, called dysbioses, that affect the onset and progression of diseases. We use next-generation sequencing, metagenomics approaches, ecological principles, and translational mouse models to fully understand shifts in microbial community composition, organization, and function in the hopes of developing personalized, microbiota-based therapeutics and practices. Current major and overlapping areas of study include:
- Assessing changes and mechanisms of the gut microbiota associated with surgery and surgical outcomes.
- Evaluating the efficacy of disrupting quorum signaling as a targetable microbiota therapeutic approach.